The Aims of the RTG 2978
GI cancers harbor a tremendous tumor cell intrinsic- and extrinsic potential to adapt to therapy-induced stresses, thus causing treatment failure. We hypothesize that mechanistic insights into therapy-induced adaptation will provide novel treatment strategies to combat GI cancer.
Scientifically, we aim to
- understand tumor cell-intrinsic, microenvironmental and systemic adaptation to therapy in BTC, CRC, HCC and PDAC.
- exploit therapy-induced adaptation to pioneer novel treatment concepts for GI cancer.
Moreover, our RTG 2978 offers an interdisciplinary translational qualification program which comprises the following educational objectives:
- To foster the scientific and translational impact of the doctoral projects conducted in the framework of the RTG 2978.
- To address existing structural gaps by equipping next-generation-scientists with theoretical and practical expertise tailored to GI cancer research.